Interested in learning how the CEPT strategy maintains cellular structure of hPSCs under stressful conditions?

Efficient cryopreservation is essential for cell scale-up, high-throughput screens, and cell therapy applications. Human pluripotent stem cells (hPSCs) are highly sensitive to stresses in the culture environment. A hyperactive ROCK pathway induces apoptosis and anoikis of hPSCs during cell dissociation, yielding low cell viability, particularly after single-cell dissociation and/or cryopreservation. Fill out the form to download this research spotlight highlighting the 2021 Nature Methods publication by Chen et al.

This research spotlight summarizes the superior cryoprotective capacity of the CEPT method to improve the survival and functionality of preserved hPSCs and differentiated cell types over other strategies. 

To learn more about Captivate Bio’s CET Cocktail Kit of small molecules, click here.