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Over the last several years, human platelet lysate (HPL) has emerged as a superior, effective substitute for fetal bovine serum as a culture medium supplement. Platelets play an important role in tissue repair and wound healing within the body. The growth factors and cytokines naturally found in platelet-rich plasma are contained within extracted platelet lysate solution. HPL is an effective, high-protein supplement for the expansion of a variety of human cell types, including MSCs, ECs, iPSCs, T cells, and more.
Captivate Bio offers one of the largest portfolio’s of human platelet lysate products which enables unparalleled cell growth for stem cells and is among one of the most cost effective and natural way of growing cells. HPL is currently available in research and clinical grades, as well as pathogen inactivated and gamma irradiated formats. Brands include PLTMax®, PLTGold®, and ELAREM™ human platelet lysate.
Human platelet lysate may retain many of the clotting factors found in raw platelets which can trigger a clot-like reaction when supplemented in cell culture media. Adding a small concentration of heparin, an anticoagulant, minimizes clotting during cell expansion. Heparin-free human platelet lysate is manufactured without any xenogenic components and no anticoagulant is needed.
*Recommendations are provided as an informational guide only, we encourage testing and validating media and supplements based on cell type and application. Please contact our Customer Service team to request a sample.
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