Research Areas
The ability of stem cells to self-renew and differentiate into other types of specialized cells make them highly valuable tools in several therapeutic applications. Stem cells are found in all developmental stages from embryonic stem cells to adult stem cells including pluripotent stem cells and mesenchymal stem cells.
Captivate Bio’s growing portfolio of cell culture media, small molecules, recombinant proteins, and our new custom stem cell modeling services offers powerful options for scientists looking to advance their studies in stem cell and therapeutic research.
Pluripotent stem cells (PSCs) are cells that can self-replicate in an undifferentiated state indefinitely as well as differentiate into most, if not all, cells of the body. Maintaining high-quality PSCs – both embryonic stem cells (ESC) and induced pluripotent stem cells (iPSCs) – is dependent on consistent, defined culture conditions.
Captivate Bio offers a diverse portfolio of products and services including serum-free basal media formulations, cytokines and growth factors, small molecules, and custom reprogramming and differentiation services.
Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including bone (osteoblasts), cartilage (chondrocytes), muscle (myocytes), and adipose tissue (adipocytes). Advancements in MSC-based research are shedding light on how these cells may be used in future therapeutic applications, such as wound healing, graft-versus-host disease, or treatment of stroke. We offer a niche portfolio of media, supplements, sera and FBS substitutes, specifically designed for those working with MSCs.
Hematopoietic stem cells (HSC) are defined by their ability to self-renew and differentiate into all cell types within the blood lineage. HSCs can be isolated from bone marrow, peripheral blood, and cord blood, and expanded in culture in the proper microenvironment and culture system. We offer a reprogramming services, custom media services, cell culture media and salt solutions, UM171, Nicotinamide, and more small molecules for HSC workflows.
iPSC-derived natural killer (NK) and T cells have provide a next-generation toolset for understanding cancer and disease pathology as well as developing successful immunotherapies. Methods to promote differentiation of iPSCs to NK cells provides useful tools for research into the basic biology of these cells and for developing adoptive immunotherapy for cancer treatment. Choose from our unique portfolio of media and reagents to facilitate the generation of NK cells as well as therapeutic research utilizing T cells.
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Stem cell research has immense potential and narrowing down protocols and methods can seem daunting. Part of that process includes identifying the exact product or formulation you need for your specific cells, which may not be available off-the-shelf. From media formulations and small molecules to reprogramming and differentiation services – we can help.