My Cart
Small Molecules

Small Molecules

A growing number of small molecules have been identified to maintain the self-renewal potential of stem cells, to induce lineage differentiation, facilitate cellular reprogramming, and support cell cryopreservation across a wide range of applications including 3D modeling as well as cancer, diabetes, neuronal, and cardiovascular research.

Captivate Bio’s portfolio of small molecules for stem cell research are powerful tools capable of modulating and fine-tuning key pathways and targets within a cell. All our small molecules are rigorously tested by liquid chromatography and mass spectrometry as well as third-party validated to guarantee highest purities and chemical structure consistency.

Captivate Bio small molecules for hpsc stem cell research
Shop By
Shopping Options
Price
  1. $0.00 - $99.996items
  2. $100.00 - $199.9912items
  3. $200.00 - $299.992items
  4. $400.00 - $499.991 item
  5. $500.00 - $599.991 item
  6. $900.00 and above1 item
Captivate Bio's CET Cocktail Kit

Minimize cellular stress with Captivate Bio’s CET Cocktail

Captivate Bio’s CET Cocktail Kit is comprised of the small molecules used in the CEPT method: Chroman 1, Emricasan, and Trans-IRIB (CET). As the first to market, the CET Cocktail Kit enhances stem cell survival and address the key challenges in cell recovery.

The CET Cocktail Kit can be used for routine long-term passaging, cryopreservation, single-cell cloning, and organoid formation.

Explore the CET Cocktail

Items 11-20 of 24

Product List

Set Descending Direction
per page
Page
  2. LDN193189 (HCl) Small Molecule
    LDN193189 (4HCl)
    View Product
    LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.
  3. PD 0325901 chemical structure
    PD0325901
    View Product
    PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
  4. Repsox Small Molecule
    RepSox
    View Product
    RepSox is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox was found to replace the function of Sox2 to induce reprogramming of iPS cells.
  5. Retinoic Acid Small Molecule
    Retinoic Acid
    View Product
    Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.
  6. SANT-1 Small Molecule
    SANT-1
    View Product
    SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
  7. SB203580
    SB203580
    View Product
    SB203580 is a selective ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a / p38 and SAPK2b / p38β2. Enhances the growth of mouse ES cells and enhances differentiation of cardiomyocytes from human ES cells.
  8. SB431542 Small Molecule
    SB431542
    View Product
    SB431542 is a potent small molecule inhibitor of TGF-β signaling. Used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Replaces SOX2 in reprogramming of fibroblasts into iPSCs.
  9. Thiazovivin Small Molecule
    Thiazovivin
    View Product
    Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.
  10. Trans-ISRIB
    Trans-ISRIB
    View Product
    An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
    Size: 10 mg
Page

Custom Reagent Sourcing

If you can’t find what you need on our website, our team can help identify and deliver unique small molecules, cytokines, and growth factors that meet your requirements, timeline, and budget. Let Captivate Bio be your first stop in providing access to thousands of research and GMP grade reagents.

Contact our team today to get started.

Contact Us