A83-01 s a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor. A83-01 molecule facilitates stem cell reprogramming and differentiation of hPSCs. A83-01 is supplied as a lyophilized powder.

Accutase® Cell Detachment Solution is a ready-to-use liquid consisting of a proprietary mixture of proteolytic and collagenolytic enzymes for use in dissociation of cells from standard and adhesion-coated plasticware. Ideal replacement for trypsin and for use with stem cells including MSCs and hPSCs.

BIRB796 is a highly potent inhibitor of p38 MAPK that enhances stem cell activity of cultured umbilical cord blood-derived hematopoietic cells. BIRB796 can be used in protocols for the chemical reprogramming of somatic cells to iPSCs.

CHIR99201 potentiates self-renewal of human and mouse embryonic stem cells and enhances reprogramming of somatic cells into stem cells. CHIR99201 also augments the differentiation potential of mesenchymal stem cells.

DMEM, High Glucose is a widely used basal medium for supporting the growth of many different mammalian cells. This formulation contains high glucose, L-glutamine, sodium pyruvate, and sodium bicarbonate.

ELAREM Prime is an affordable, research-grade human platelet lysate designed specifically for the academic researcher who is looking to move away from using FBS in cultures. Research-grade, heparin required, EU origin.

ELAREM™ Ultimate-FDi is a virus-inactivated and fibrinogen-depleted human platelet lysate. Ultimate-FDi is a clinical-grade supplement suited for therapeutic cell manufacturing requiring gamma-irradiation and viral panel testing. GMP-grade, Drug Master File, and US origin.

IWP 2 is a potent inhibitor of Wnt processing and secretion (IC50 = 27nM). IWP 2 inactivates PORCN, a membrane-bound O-acyltransferase (MBOAT), and selectively inhibits palmitoylation of Wnt. IWP-2 has also been used in protocols to reprogram somatic cells to chemically-induced PSCs.

IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.

MCDB 131 medium is commonly used in definitive endoderm differentiation of human pluripotent stem cells (hPSCs) as well as a basal medium for MSC differentiation.