Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.

RPMI 1640 Medium was originally developed to culture human leukemic cells in suspension and as a monolayer. This formulation is modified with L-glutamine and Phenol Red.

RPMI 1640 Medium was originally developed to culture human leukemic cells in suspension and as a monolayer. This formulation is modified without glutamine or glucose and with Phenol Red.

SB203580 is a selective ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a / p38 and SAPK2b / p38β2. Enhances the growth of mouse ES cells and enhances differentiation of cardiomyocytes from human ES cells.

SB431542 is a potent small molecule inhibitor of TGF-β signaling. Used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Replaces SOX2 in reprogramming of fibroblasts into iPSCs.

Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.

An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail¹.
Size: 10 mg

Triiodothyronine Salt is an analog of thyroid hormone that selectively binds to and activates β1 thyroid hormone receptor (TRβ1). This binding, in turn, regulates functions such as growth, metabolic activity, and differentiation. Stimulates respiratory activity at the mitochondrial level.

XAV939 is a potent tankyrase (TNKS) inhibitor. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols.